منابع مشابه
Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer
The risk of onset of cancer is influenced by poorly controlled chronic inflammatory processes. Inflammatory diseases related to cancer development include inflammatory bowel disease, which can lead to colon cancer, or actinic keratosis, associated with chronic exposure to ultraviolet light, which can progress to squamous cell carcinoma. Chronic inflammatory states expose these patients to a num...
متن کاملBioactive Natural Matrices and Compounds
The demand for healthy ingredients and a natural way of preventing diseases is contributing to the increased use of natural matrices. There has been a lot of research indicating that general antioxidant properties are not the contributing factors to improving human health but rather the antioxidant properties of specific compounds involved in specific cell signaling mechanisms that need to be e...
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In recent years, the potential of marine natural products as anticancer agents, specifically for breast cancer, has been examined. The sea cucumber (Holothuroidea: Echinodermata) is known to contain triterpene glycosides, which have shown anticancer or cytotoxic activity. In this research, molecular docking of selected sea cucumber bioactive compounds was conducted on five receptor targets that...
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Combination therapy consists in the simultaneous administration of a conventional chemotherapy drug (or sometimes, a radiotherapy protocol) together with one or more natural bioactives (usually from plant or fungal origin) of small molecular weight. This combination of anticancer drugs may be applied to cell cultures of tumor cells, or to an animal model for a cancer type (or its xenograft), or...
متن کاملNanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention
Pomegranate polyphenols are potent antioxidants and chemopreventive agents but have low bioavailability and a short half-life. For example, punicalagin (PU), the major polyphenol in pomegranates, is not absorbed in its intact form but is hydrolyzed to ellagic acid (EA) moieties and rapidly metabolized into short-lived metabolites of EA. We hypothesized that encapsulation of pomegranate polyphen...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2011
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2011.03938.x